ellaOne (Ulipristal 30 mg) is the new and improved version of RU 486. Its mechanism of action is similar in that it blocks the hormone progesterone from its effect of maintaining the endometrial lining of the uterus.
Recall that while estrogen is key to stimulating the growth and development of a new uterine lining (endometrium), progesterone is tasked with maintaining the structural integrity of that lining (to which the embryo attaches). In a normal menstrual cycle, the former egg follicle, the corpus luteum, produces progesterone and dies if no embryo has been produced. Thus the definition of menstruation is progesterone withdrawal from an estrogen-primed uterus.
If an embryo happens to be nestled in that endometrium and ellaOne is taken to block the effects of progesterone, the endometrium will break down, flushing the embryo out in the process.
Whereas RU 486 was taken as a morning after pill, ellaOne can be taken several days later.
The FDA is set to hold hearings on ellaOne this coming June 17. At those hearings we will hear of how this drug is not an abortifacient, that it is meant as emergency contraception to prevent pregnancy.
Enter the verbal engineering.
The pro-aborts have actually outrun their own verbal engineering, which is always engaged in as the necessary pre-requisite to social engineering. The American College of Obstetrics and Gynecology defines pregnancy as the implantation of the embryo. It used to be defined as conception. However, this definitional change does have a curious logical coherency.
In vitro fertilization (IVF) continues to spawn all manner of derivative evil. It is because of IVF that the definition of pregnancy was changed. A woman is said to be pregnant when she has conceived in her body (in vivo). However, when a woman donates eggs, which are then fertilized in a petri dish (in vitro), the woman is not said to be pregnant, and rightly so. She may have 30-40 live babies in their embryonic stage in a petri dish, but her body remains without child. Thus, a mother of 40 can remain never having been pregnant.
The definition needs to be reworked, back to conception, but including IVF. I propose the following:
Pregnancy: The status of a woman whose body possesses nascent human life from the moment of in vivo conception, or has received nascent human life through artificial implantation.
It makes a difference.
Through the current IVF-inspired definition, RU 486 is held to be an emergency contraceptive. Taken early enough, ellaOne could fit that same definition. However, ellaOne can be taken when the embryo has already implanted, running up against even the current and tortured definition of pregnancy. As such, there can be no doubt that ellaOne is an abortifacient. Thus the pro-aborts are now hard-pressed to find verbal engineering sufficient as to give them cover. However, what they lack in the way of rhetorical cover, they may well gain by brute political force.
FDA is always at the mercy of Congress and the White House for funding. With the demonic trinity of Obama-Reid-Pelosi, do they dare reject this new drug? It’s a dilemma to be certain.
November is coming.
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Just wanted to say, I don’t think RU486 is the drug you mean to contrast with this EllaOne. It’s not the “morning after pill” and no one claims RU486 is a mere contraceptive, AFAIK. That’s the “Plan B” you mention in your title which is a different drug altogether. I really wouldn’t want that error to be what somebody uses in an attempt to discredit your actual points.
Technical correction — Plan B and RU486 are differently drugs, intended to work differently.
RU486 contains synthetic steroid mifepristone, and is indeed an arbortificent, as you say.
Plan B (which I myself have kept around the house for years, just in case) is progestin hormone levonorgestrel, intended prevent ovulation. However, if an egg is already fertilized, it still MIGHT cause an abortion by altering the uterine lining and preventing implantation, though this is still not conclusively determined (though for some people, the chance if this is an unacceptable risk).
Some Catholic hospitals dispense plan B to rape victims only if a woman takes a test to find out if ovulation has occurred — http://ncronline.org/news/catholic-journal-says-plan-b-does-not-cause-abortions
EllaOne will now be marketed as Ella in the US. It is Ulipristal acetate, which is a direct analog of mifepristone, or RU486.
EllaOne is a selective progesterone inhibitor which, at the 30mg dose given, will usually work by preventing implantation.
Ella One will not inhibit ovulation to any meaningful extent when given after the peak of luteinizing hormone. This means it will not have the effect that pro aborts pretend it will have, during the time of greatest fertility. A most significant portion of its efficacy is attributable to an embryocidal effect by inhibiting implantation.
Doses may be accumulated for home abortions at later stages of development, since this drug is a direct analog of mifepristone. Incidentally, the latter drug has been in use in China as a morning after pill.
The dose of EllaOne (ulipristal acetate) needed to prevent ovulation is quite a bit higher than 30mg dose used as a morning after pill, but somewhat below the dose which will reliably kill embryos after implantation.
Ella One is contraindicated in pregnancy or suspected pregnancy. However it appears that the FDA will not be requiring a pregnancy test before the drug is given.
There is next to no data on the effect of EllaOne in pregnancy. In phase III trials, 16 of the pregnant women aborted, 6 of the women miscarried, two of the women had unknown results, and four “normal” deliveries occurred.
Not much information is needed about drugs which are to be used only in women, who continue to occupy second class status in the Western world.